Tumors employ multiple mechanisms to evade immune surveillance.
As a successful pathogen, HSV has multiple mechanisms to evade such host responses.
Consequently, N meningitidis uses multiple mechanisms to avoid being killed by antimicrobial proteins, phagocytes, and, crucially, the complement system.
First, although the immune system has evolved multiple mechanisms to recognise and eliminate neoplastic cells (Senovilla et al, 2013), tumours emerge within the patient when they escape immune surveillance (Mittal et al, 2014).
The results reveal how mammalian telomeres use multiple mechanisms to avoid DNA damage surveillance and provide an explanation for the induction of replicative senescence and genome instability by shortened telomeres.
Collectively, the FA network employs multiple mechanisms to protect CFSs, and our study reveals a novel function of FANCM to remodel forks at the sites containing DNA secondary structures through its translocase activity to maintain CFS stability.
Protein toxins secreted from pathogenic bacteria and venomous animals rely on multiple mechanisms to overcome the cell membrane barrier to inflict their virulence effect.
Mutant ARs exploit multiple mechanisms to resist hormone ablation, including alterations in ligand specificity, target gene selectivity, chaperone interaction and nuclear localization.
HIV-1 has evolved multiple mechanisms to evade readily elicited antibodies against more open Env conformations.
Cancer cells have evolved multiple mechanisms to disable programmed cell death to support their survival and proliferation.
Interestingly, influenza virus uses multiple mechanisms to evade and inhibit the innate immune response of the host.
