This drug is unique because it has multiple mechanisms of action, including blood vessel dilation and a calcium channel blockade.
Edaravone is a lipophilic drug with multiple mechanisms of action.
The MTLD can shed light on the multiple mechanisms of action of drugs or natural products.
Multiple mechanisms of action for infant formula ingredients with probiotic activity appear to exist.
Such smart skin substitutes may use different and multiple mechanisms of action for acute and chronic wounds.
Thus, SATB1 affects the expression of various genes by multiple mechanisms of action, involving three-dimensional chromatin architecture.
There are multiple mechanisms of action for NSAID-induced angioedema, including COX-1 inhibition leading to production of the inflammatory mediators, cysteinyl leukotrienes, and IgE-mediated hypersensitivity [35].
OVs are cytotoxic and target cancers via multiple mechanisms of action while at the same time exploiting validated genetic pathways known to be dysregulated in many cancers.
The empirical nature of the discovery of new AEDs in the last three decades coupled with their multiple mechanisms of action explains their diverse chemical structures.
All together, this approach represents a unique targeted nanoparticle design with remarkable selectivity towards pancreatic cancer and multiple mechanisms of action.
Metronomic administration of oral chemotherapy also represents a promising therapeutic approach for select patients with MBC, inhibiting tumor progression through multiple mechanisms of action.
