Sentence examples for multiple mechanisms as from inspiring English sources

Of these compounds, compound 5a showed the best inhibitory activity against MGC-803 cells (IC50 = 9.78 μM), induced apoptosis through multiple mechanisms, as well as inhibited migration of MGC-803 cells.

Heavy metals cause toxicity in oilseed crops via multiple mechanisms, as symptoms are highly crop, metal, and dose specific.

Calcium addition also enhanced the expression of Dsg3, as we reported previously.8 We observed that the calcium-induced pERM could only be partially abrogated by PKC inhibition (Supplementary Figure 8b, plus Ca2+) and this incomplete inhibition suggests that multiple mechanisms (as shown in Figure 6c), either mediated by calcium or Dsg3, are involved in ERM phosphorylation.

By considering multiple mechanisms as we 'climb the social ladder', we can test whether the transitions from solitary to simple sociality to complex sociality represent incremental changes or genetic revolutions.

We conclude that drought-tolerant accessions such as Vagad must have developed multiple mechanisms as adaptive behavior against drought.

ApoE plays an important role in mediating Aβ clearance through multiple mechanisms, as depicted in Figure 1.

The amino acid sequence and structural observations did not apply uniformly to all PSC patients, suggesting multiple pathogenetic mechanisms, as might be expected for a disease with the clinical heterogeneity observed in PSC.

The plasma membrane can compensate for mechanical stress by multiple mechanisms such as unfolding and by increasing lipid trafficking to the plasma membrane [ 64].

Together, these observations, especially in key virulence factors, reveal that multiple mechanisms, such as point mutations, gain or loss of genes, as well as HGTs, contribute to the substantial phenotypic diversity of these versatile subspecies in various hosts.

Hypericin acts as an anti-depressant via multiple mechanisms such as γ-aminobutyric acidA (GABAA) receptor and 5-hydroxytryptamine1 (5-HT1) receptor binding, inhibition of dopamine-β-hydroxylase and suppression of glutamate release [ 1, 3].

Resistance to therapy is often the result of multiple mechanisms such as overexpression of anti-apoptotic proteins, such as Bcl-2 family members (Bcl-2, Bcl-xL, Bcl-w, Mcl-1), or the inhibitors of apoptosis proteins (IAPs), such as survivin or XIAP.