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The multiple mechanism of action for 5-HT1B/1D receptors includes vasoconstriction, inhibition of the release of vasoactive neurotransmitters by trigeminal nerves as well as inhibition of nociceptive neurotransmission [13, 14].
The multiple mechanism of action for 5-HT1B/1D receptors includes vasoconstriction, inhibition of the release of vasoactive neuropeptides by trigeminal nerves as well as inhibition of nociceptive neurotransmission [13, 14].
The above observation suggested multiple mechanism and ulcer protective action of methanol leaf extract of P. foetida.
Recurrent uveitic episodes, multiple mechanism, and the complications associated with uveitis make surgical management of UG challenging.
This suggests that this triterpene could manifest its effect on both constitutive and inducible STAT3 activation through multiple mechanism(s).
This can be explained by the multiple mechanism of action of these compounds on several targets with the consequent therapeutical efficacy.
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