Given our finding across multiple populations and matching results from a different seed source, it is unlikely that population-level differences are sufficient to account for the discrepancies in results between these findings and those of Matsunaga et al. [8].
Furthermore, organizing the T and π configurations into multiple stages will retain the final matching results but will change the Q factor.
In a hypothetical ideal case where the target sequence matches exactly the reference sequence, and read sequencing is error free, we will not have any misaligned reads; Pmis=0, and Puq is maximized (multiple matches are only resulted from reference similarities).
For the trnH-psbA spacer there was also no statistical difference between using partial sequences versus complete sequences in the searches: partial sequences resulted in 28.6% multiple matches while complete sequences resulted in 26.5% multiple matches (Chi-square 0.04; df = 1; p = 0.8).
Fig. 22 SIFT matching results.
In the human genome, for sequences less than 8 nt in length, the most common result was multiple matches, whereas at 8 nt and above, a unique, correct match was the most likely result.
However, the reads deriving from the core repeats had multiple matches and were eliminated, thus resulting in the coverage dip in the corresponding region.
On the other hand, permissive thresholds that produce more sensitive probabilistic models and improve the recovery of the known components of a given pathway, typically also result in multiple matches from other pathways.
The number of genes resulting in one match or in multiple matches are indicated.
If more than one match results for a particular teacher or school, the match that yields the highest utility for the entity with the multiple matches is observed in the data.
