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Therefore, multiple markers need to be analyzed simultaneously in order to distinguish these innate cell populations.
To achieve a greater predictive value, multiple markers need to be examined and correlated with the response of tumor cells to chemotherapy.
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Single biomarkers identified thus far lack sufficient sensitivity and specificity and it is likely that multiple markers will need to be employed simultaneously.
Although none of the many biomarker profiles suggested to date optimally predicts the disease, the latter study demonstrates one of the novel approaches being taken to allow early detection and suggests that multiple markers will need to be included to develop a useful predictive test.
Because multiple markers are needed to distinguish each founder, the effective founder-ascertainment resolution of MUGA is approximately 1 Mb.
At this time, we can conclude that already identified single biomarkers show a lack of sufficient sensitivity and specificity in EC, and that it is likely that multiple markers will be needed simultaneously to address the diagnosis and prognosis of EC [ 3].
Despite the success of single diagnostic markers, there is a pressing need for multiple markers.
However, increasingly, there is recognition of the complex nature of tumor resistance to chemotherapy and the need for multiple markers to stratify patients according to their likelihood of response to chemotherapy.
Despite a reasonably useful sensitivity and specificity profile, the fact that prenatal screening tests are typically usable at a relatively narrow gestational window and the need to combine multiple markers have prompted workers to explore new approaches for noninvasive prenatal diagnosis.
The author adeptly targets a need for using multiple markers across multiple individuals for proper inference.
In an eight-way cross, the genotypes at multiple markers (at a minimum three) are needed to distinguish among the founders.
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CEO of Professional Science Editing for Scientists @ prosciediting.com