Sentence examples for multiple malignancies including from inspiring English sources

High VEGFA levels predict a poor prognosis in multiple malignancies, including haematological malignancies.

Bcl-2 overexpression plays a central role in resistance to chemotherapy in multiple malignancies including HB [ 13].

Emerging evidence has demonstrated that Neutrophil gelatinase-associated lipocalin (NGAL) is up-regulated in multiple malignancies, including oesophagus cancer, and plays a critical role in tumorigenesis and progression.

Presently, small-molecule inhibitors of the PI3K pathway are in clinical development to treat multiple malignancies, including BC [ 41, 42], and several cross the blood-brain barrier.

The link between miRNAs and metastasis in multiple malignancies including PDAC is reported to be the ability of some miRNAs to epigenetically modulate metastasis-related gene expression and vital molecules of signaling pathways.

The level of vascular endothelial growth factor (VEGFA) at time of diagnosis is an independent prognostic factor for treatment outcome in multiple malignancies, including (paediatric) acute myeloid leukaemia (AML) (Aguayo et al, 1999; de Bont et al, 2002).

This study demonstrated activity of carfilzomib in multiple hematologic malignancies, including bortezomib-resistant multiple myeloma, confirmed sustained inhibition of the chymotrypsin-like activity of the proteasome subunit, and established the drug and the schedule as safe.

Also survivors of childhood STS, osteosarcoma, and Ewing sarcoma have been shown to be at increased risk of multiple primary malignancies, including bone sarcomas and STS (Heyn et al, 1993; Pratt et al, 1997; Neglia et al, 2001; Paulussen et al, 2001; Bacci et al, 2005; Cohen et al, 2005; Bassal et al, 2006).

Though Trop-2 has been shown to be an excellent candidate antigen for targeted immunotherapy in multiple gynecologic malignancies including EEC [ 24], uterine papillary serous carcinomas [ 22], chemotherapy-resistant [ 23] and sensitive ovarian carcinomas [ 32], and cervical carcinomas [ 25], this is the first proof that Trop-2 overexpression can also prognosticate patient outcome in EEC.

In addition, we have studied SAA protein expression and secretion in multiple primary gynaecologic malignancies including USPC and cervical cancer tumour cultures.

However, anti-tumour activity of MIRA-1 in haematological malignancies including multiple myeloma (MM) is unknown.