In this way, mRNAs bound by multiple ribosomes and hence actively translated can be isolated and distinguished from mRNAs bound by non-productive 80S ribosomes.
In this way, mRNAs bound by multiple ribosomes and hence actively translated can be isolated and distinguished from mRNAs bound by sporadic, putatively non-productive single ribosomes or ribosomal subunits.
Hafner, M. et al. Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition.
These studies revealed that individual mRNAs bind multiple SR proteins, as was also described in insect cells (Björk et al., 2009).
CAG repeat mRNAs bind to and sequester diverse proteins.
PDB Description: 50S ribosomal subunit from a crystal structure of release factor RF2, tRNAs and mRNA bound to the ribosome.
As targeting only requires partial complementarity, a single miRNA can bind multiple mRNA transcripts and each mRNA can be bound to multiple miRNAs.
A process that allows multiple mRNAs to be transcribed from a single gene.
Both cDNAs are complementary to multiple mRNAs that are differentially expressed during development.
Individual miRNAs may target multiple mRNAs.
