Studies using multiplexed virus PCR assays have detected both an increased proportion of children with single and multiple viral lower respiratory infections [ 42].
A 72-year-old patient with long history of chronic obstructive pulmonary disease and multiple fluoroquinolone treatments for recurrent lower respiratory tract infections developed fever, increased sputum production, and dyspnea.
We distinguished sepsis-related complications (secondary septic shock, acute respiratory distress syndrome or development of multiple organ failure), hospital-acquired lower respiratory tract HA-LRTT) superinfections and ICU-related complications (i.e., upper gastrointestinal bleeding, catheter-related infection, deep venous thrombosis and pulmonary embolism).
Outbred ferrets exhibit severe lethargy, fever, weight loss, and transient lymphopenia, as well as viral replication in the upper and lower respiratory tract, brain, and multiple systemic organs after infection with various strains of H5N1 virus.
In humans, HRSV infection starts in the upper respiratory tract and viral spread to the lower respiratory tract probably involves multiple rounds of infections.
Another strength is that VITALITY will examine multiple important outcomes including food allergy and lower respiratory infections.
Over the past few years, solely on the basis of clinical data, the patient had received multiple treatments with oral levofloxacin and ciprofloxacin for recurrent lower respiratory tract infections (LRTi).
In the 2 yrs prior to diagnosis, 56% of patients were consulted for respiratory complaints (26% for lower respiratory tract infections) and most of them (34%) received multiple prescriptions for oral steroids and/or antibiotics.
Multiple bacteria were defined as more than one pathogen reaching significant threshold isolated from lower respiratory tract specimen.
Human metapneumovirus (hMPV) is the second leading cause of lower respiratory infection (LRI) in children around the world and has been linked to LRI in multiple studies.
