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Multiple low density well-defined hypodense neurofibromas along the sacral plexus were seen in the pelvis on both sides (arrows) on CT scan (c).
CT characteristically shows prominent asymmetric thickening of the caecum in conjunction with multiple low density enlarged lymph nodes (Fig. 8).
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Two months after admission, CT showed multiple low-density areas in both kidneys.
Contrast-enhanced CT after the second vaccination showed multiple low-density areas in the liver tumor, indicating tumor necrosis.
Most patients have radiographic abnormalities, described on enhanced computed tomography (CT) as diffuse kidney enlargement, multiple low-density lesions or hypovascular solitary mass [ 2– 4].
Miliary hepatic TB, which has smaller tubercles, is visualized on a CT scan as multiple, low-density micronodules dispersed throughout the liver [ 60].
In a longitudinal imaging study, contrast enhancement of the renal cortex recovered after therapy in almost all patients with multiple low-density lesions [ 20▪▪].
First, the margin between affected and unaffected portions is very clearly demarcated, with this finding thought to correspond to the imaging feature of multiple low-density lesions [ 16, 18, 32].
Clinically, decreased renal function, or characteristic imaging findings such as multiple low-density lesions on contrast-enhanced computed tomography or diffuse thickening of the renal pelvic wall, are typical presenting features.
Possible reasons are that the recombination rate is higher at the chromosome ends [ 23], or that imputation works best if multiple low-density markers are present on both sides of an imputed marker.
Despite this, because much fewer assays are needed when DNA samples are pooled, it will be cost effective to use multiple low-density SNP assays such as the four P. monodon multiplexed assays already available [ 39] or high-density SNP assays when they become available.
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