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Multiple locomotor phenotypes were observed.
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The influence of multiple adaptive peaks on the divergence of locomotor phenotypes in Geophagini is compatible with the expectations of an ecologically driven adaptive radiation.
This study confirms that the diversification of locomotor phenotypes represents an important dimension of phenotypic evolution in the geophagine adaptive radiation.
We next did a series of experiments to determine if other reward, anxiety, and locomotor phenotypes were affected by mGluR5 deletion or haploinsufficiency.
(This is a major contrast to parkin expression, which rescues each of the oxidative stress, RMP and locomotor phenotypes).
Different suites of locomotor traits optimize swimming performance for different ecological conditions [ 25- 27] thus much of the observed diversity of locomotor phenotypes is likely related to ecological specialization.
Loss of function of MCHR-1 recreates the locomotor phenotypes seen in Pmch−/− mice: Mchr1−/− mice are super-sensitive to the locomotor activating effects of d-amphetamine (Smith et al., 2005).
The evolution of locomotor phenotypes was characterized by selection towards at least two distinct adaptive peaks and the early divergence of modern morphological disparity.
In this study, we show that many of the postural and locomotor phenotypes of human manganism can be replicated in a larval zebrafish model of the disease.
These augmented locomotor phenotypes contrast with the behavioral effect we see with a loss of sucrose preference in MCH ablated mice.
In fish radiations the evolution of locomotor phenotypes (i.e. post-cranial attributes) may represent an important dimension of ecomorphological diversification.
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