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These losses are often broad, and may target multiple loci, reducing the function of more than one gene.
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It might be expected that presence of multiple loci affecting WEC would reduce the selection pressure acting on each worm locus, although this is yet to be rigorously explored.
Another effect of increased recombination that may be beneficial is the reduced variation in genetic relatedness across multiple loci among colony members, which may reduce the potential for nepotism and kin conflict [ 17, 18].
Because one gets multiple generations of gene spread from a single release (due to assortment of the multiple loci) it may be possible to reduce the number of releases that need to be performed.
If the effects of increased expression extend across multiple loci, the evolution of DC will reduce the cost of loss of genes in short pathways.
The bias in real life data sets which contain multiple loci from several individual is naturally much reduced.
Both control probe sets and probe sets that mapped to multiple loci in the genome were removed from the analysis, reducing the rice dataset from 34,873 to 33,602 probesets.
The analysis restricted to the 40-kb sfl locus reduces the burden of multiple testing by several orders of magnitude, but also fails to identify a significant association.
This is accomplished by reducing the dimensionality of the multilocus data where genotypes from multiple loci are pooled into high-risk and low-risk groups, depending on whether they are more common in affected or in unaffected individuals [ 4, 5].
Individual clusters which mapped to multiple loci and/or arose from cluster assemblies producing multiple contigs were omitted to reduce the mapping of clusters potentially containing EST reads of duplicate genes and closely related members of gene families.
Multiplex PCR is an extension of the standard PCR protocol in which multiple loci are amplified simultaneously in order to save time, improve throughput, and reduce the total cost of reagents.
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