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The lineage of PB 1121 (Fig. 2) clearly shows that as many as 13 rice varieties/enhanced germplasm, including the traditional Basmati rice varieties such as Basmati 370 and Type 3 were used to bring together the favorable alleles at multiple loci for agronomic, grain and cooking quality characteristics in development of PB 1121.
Multiple loci for MHC Class II have a profound impact on peptide binding and anti-infections.
With multiple loci for MHC Class II, the frog has an ability to battle constantly intracellular infection, such as virus.
In addition to environmental factors, interactions among multiple loci for the expression of quantitative traits may be involved.
Multiple loci for MCH have been identified in human GWAS [ 17- 19] (Methods, Additional file 2: Table S2).
The use of multiple loci for strain identification is preferred [ 23, 25] as a single locus cannot differentiate all the strains.
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In order to obtain clear sequences for potentially multiple loci of BRK1 for these species, the PCR products were cloned into the blunt end vector pJET1.2/blunt according to the manufacturer's protocol (CloneJET™ Molecular Cloning Kit, Thermo Scientific, St. Leon-Rot, Germany).
Such an approach could be especially powerful in the case of traits conferred by multiple loci of small effect size, for example, removing deleterious mutations that are predicted to accumulate during domestication and breeding.
This approach has been employed to compare maximum likelihood (ML) trees describing multiple loci from the genome of, for example, Borrelia burgdorferi [64], Neisseria meningitidis [66] and Streptococcus uberis [67].
The haplotype analysis revealed that U.S. weedy rice retained large blocks of linkage disequilibrium for the multiple loci from the wild relatives and also incorporated haplotypes from cultivars.
Contrary to the simple stochastic model, the second and last cases require multiple loci changes for a single DE gene.
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