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These loci will not be analyzed further here, but note that the presence of multiple loci encoding HET proteins was already described in a number of fungal species, including N. crassa and Aspergillus fumigatus [27], [28].
Strikingly, these analyses suggest possible horizontal gene transfer (HGT) events in multiple loci encoding virulence factors, including O-antigen and pertussis toxin (Ptx).
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In the present studies, HERV-W env encoding alleles were principally derived from the 7q21.2/ERVWE1 locus in autopsied brain samples from both MS and non-MS persons; while in primary neural cells and healthy brain specimens (fetal and adult), multiple loci encoded HERV-W env alleles.
Either a single var2csa gene locus encodes a dimorphic series of allelic variants, or multiple loci encode related var2csa-type genes, each having a particular variant of the DSM.
Our findings provide a highly relevant case study of a duplication leading to multiple functional loci encoding a gene with important adaptive traits in onion.
To further corroborate this phenomenon, these data were compared with loci encoding multiple Unigene and/or full length cDNA sequences possessing unique canonical tags (Additional file 1).
To identify gene loci encoding MFS proteins, multiple TBLASTN searches were performed on assembly (version 21) of the C. albicans genome using well known MFS proteins as queries.
Also abundant in our datasets were loci encoding two transmitter domains and multiple receiver domains.
To identify gene loci encoding ABC proteins in the fungal genomes, multiple tblastn and blastp searches against selected genomes were performed at the website of the Fungal Genomics Program of the Department of Energy Joint Genome Institute JGII) [ 25].
To identify gene loci encoding ABC proteins in the fungal genomes, multiple blastp and tblastn searches against selected genomes were performed either at the National Center for Biotechnology Information website or at the website of the Broad Institute.
In Arabidopsis, there are four TAS gene loci encoding ta-siRNAs.
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