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Either a single var2csa gene locus encodes a dimorphic series of allelic variants, or multiple loci encode related var2csa-type genes, each having a particular variant of the DSM.
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These loci will not be analyzed further here, but note that the presence of multiple loci encoding HET proteins was already described in a number of fungal species, including N. crassa and Aspergillus fumigatus [27], [28].
In the present studies, HERV-W env encoding alleles were principally derived from the 7q21.2/ERVWE1 locus in autopsied brain samples from both MS and non-MS persons; while in primary neural cells and healthy brain specimens (fetal and adult), multiple loci encoded HERV-W env alleles.
Strikingly, these analyses suggest possible horizontal gene transfer (HGT) events in multiple loci encoding virulence factors, including O-antigen and pertussis toxin (Ptx).
Our findings provide a highly relevant case study of a duplication leading to multiple functional loci encoding a gene with important adaptive traits in onion.
Nevertheless, both loci encode potentially transcribed genes.
It is a widespread feature of sequenced fungal genomes to contain multiple loci that encode similar plant cell wall degrading enzymes.
To further corroborate this phenomenon, these data were compared with loci encoding multiple Unigene and/or full length cDNA sequences possessing unique canonical tags (Additional file 1).
To identify gene loci encoding MFS proteins, multiple TBLASTN searches were performed on assembly (version 21) of the C. albicans genome using well known MFS proteins as queries.
CNV of a 31 kb repeat segment observed in different haplotypes of the Rhg1 locus encode multiple gene products in soybean cyst nematode (SCN -resistant varietieSCN -resistant
Also abundant in our datasets were loci encoding two transmitter domains and multiple receiver domains.
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