Signatures of locally varying selection are clearly seen at multiple loci, and the most geographically divergent genomic locus is the gdv1 gene and the large 3′-adjacent intergenic sequence.
Both quantitative (e.g., height) and qualitative (e.g., eye color) traits may be influenced by multiple loci and these loci may interact with one another and may not follow the simple rules of Mendelian dominance.
In this study, we developed a new systematic method for mapping multiple loci and applied the proposed method to construct a genetic network for rheumatoid arthritis (RA) via analysis of 746 multiplex families genotyped with more than five thousands of genome-wide SNPs.
Moves beyond traditional views of technological change by looking at multiple loci and their respective roles and contributions to technological development and innovation practices.
The program STRUCTURE analyzes allele frequencies across multiple loci, and assigns individuals to appropriate populations [30].
The spatial relationships of the MaSp1 multiple loci and MaSp2 locus in Latrodectus genomes are unknown.
Is HMS caused by only a few factors of large effect or does it have a more complex basis, involving multiple loci and epistatic interactions?
Indeed, much effort in recent years has been devoted to identifying genes associated with hybrid incompatibilities, often with limited success, suggesting that hybrid sterility and inviability are frequently caused by complex interactions between multiple loci and not by single or a small number of gene pairs.
We consider a viral genome length of L = 100 nucleotides, which spans the experimental fitness landscape [37] (Methods) and captures expected epistatic interactions between multiple loci and is also similar to the genome lengths examined in the experiments we consider [36] (see below).
Moreover, in contrast to previous reports that relied on the analysis of each locus separately, we used PCA and CA methods that can grasp the different contributions of multiple loci, and therefore allow a true genome-wide comparison of the different populations.
Similarly, DSP1 binds polytene chromosomes at multiple loci and partially co-localizes with PH [ 31].
