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The multiple local alignments of putative ar-C sequences were obtained using the CHAOS/DIALIGN algorithms [26], and then visualized with BioEdit (written by Tom Hall, Ibis Biosciences, Carlsbad, CA, USA).
The LocARNA in principle can compute structure-based multiple local alignments, but the current implementation of LocARNA doesn't support the output of such multiple local alignments.
In this paper we present GASOLINE, a Cytoscape app for multiple local alignments of PPI (protein-protein interaction) networks.
For each of these pairs, using the location and orientation of the mapped read, Pindel searches for the paired unmapped read ('split' read) by performing multiple local alignments.
In this paper, we presented GASOLINE, an app for Cytoscape 3 for computation and visualization of multiple local alignments of protein-protein interaction networks.
For each pairwise comparison of the query protein to a database protein, the algorithm produces multiple local alignments of the surface regions that are found in both; no attempt is made to align the proteins globally and similar folding is not a requirement for a relationship between the two proteins.
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ChIPMunk [ 11] searches a gapless multiple local alignment using a greedy algorithm to deal with a large set of inputs.
"Here, we describe a Cytoscape app implementing the GASOLINE algorithm for multiple local alignment of PPI networks".
To the best of our knowledge, it is the first Cytoscape plugin for computation and visualization of multiple local alignment of biological networks.
ChIPMunk searches for the gapless multiple local alignment with the highest Kullback Discrete Information Content (KDIC) [ 19], under the common assumption of independence for neighboring nucleotides.
Here, we describe a Cytoscape app based on GASOLINE (Greedy And Stochastic algorithm for Optimal Local alignment of Interaction NEtworks), a greedy and stochastic algorithm for multiple local alignment of PPI networks, introduced in.
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