Twelve studies (32.4% of 37 studies) validated information from multiple, linked administrative data sources; five of these studies included inpatient records (13.5% of 37 studies) and five included outpatient records as one of the databases.
To determine better the incidence and outcomes of CKD across this or other regions, including its association with Indigenous status, studies using linked data from multiple sources will be required.
Our ability to collect data on multiple measures by audit, survey, and use of administrative data with good participation rates, high agreement rates between chart assessors, high rates of completion for surveys, and little objection to data linkage, shows that the collection of linked data from multiple sources is both acceptable and feasible.
Because of the interoperable and distributed design, multiple instances of services running at multiple places could communicate and generate dynamically linked data.
Nevertheless, there is an added value of merging both technologies for independent deployments of multiple services, able to dynamically generate linked data with dereferenceable links.
Pathway Commons is a publicly available resource that aggregates and integrates pathway data from multiple organisms and databases into a common BioPAX language linked data representation.
The linking component of linked data, however, puts an additional focus on the integration and conflation of data across multiple sources.
Briefly, given genotyping data at multiple linked loci, we estimate the unobserved haplotypic phase and impute any missing calls by combining information about population haplotypic frequencies with information about the neighbouring loci.
A large, patient-centric data network including multiple, linked databases designed for safety and outcomes research in the Netherlands were linked to data from a regional cancer registry (van Herk-Sukel et al, 2010).
