Sentence examples for multiple linked SNPs from inspiring English sources

The presence of multiple linked SNPs is a prerequisite for the recognition of phylogenetically distinct lineages, and we show here that these morph-associated SNPs define a small number of morph-associated haplotypes.

Multiple linked SNPs in the TRAF family member-associated NF κB activator (TANK) and TNF receptor-associated factor 6 (TRAF6) genes also gave suggestive signals of association with SLE in the combined Swedish cohort.

Enhancers have been shown to overlap multiple linked SNPs more often than expected at random [ 3, 10], suggesting that multiple enhancer variants work together in concert to alter gene expression and contribute to disease susceptibility.

Of these scaffolds 52 only could be assigned a position but not orientated, either because they carried a single uSNP or because they contained multiple tightly linked SNPs whose map order was questionable due to insufficient radiation-induced breakpoints.

Each of ten additional SNPs in the VKORC1 region (Fig.  2a) was tested to determine if it added significantly more dose variance to a multiple regression model that included one of the three linked SNPs (rs2359612), CYP2C9 *2 and *3, and non-genetic predictors of warfarin dose (Supplementary Table S3).

Since our tests are not independent, it would be useful to calculate the effective number of independent tests to illuminate the degree to which grouping linked SNPs into haplotypes reduces the problem of multiple testing.

Linked SNPs were identified using PLINK and 1000 Genomes (phase 1) variant call format files [29,57].

SNP-STR, a compound genetic marker combining a STR locus with tightly linked SNPs, is more informative than any single polymorphism.

Where possible, up to four linked SNPs were evaluated.

However, other linked SNPs may be useful in specific crosses.

Here, users can query not only the submitted SNPs, but also their linked SNPs (r > 0.8).