Through extensive medicinal chemistry probing the R1 R3 groups of the D-ring in this steroidal structure to generate a compound library, followed by multiple lines of screening studies focused on 20 candidates, VBP15 was subsequently identified as our lead compound.
Typically, HTS was performed on a panel of cancer cell lines screened with multiple compounds to generate pharmacological profiling data.
The cell line screening was assisted by M.Y.
Through this P-excision screen, we obtained multiple lines in which excision at the CG1514 insertion site had occurred, but in all cases a small fragment (25 45 bp) of residual P-element was still present at the excised locus.
In spite of multiple lines of evidence (international experience, cost benefit simulations) suggesting that universal screening for LQTS is feasible and effective, there remains considerable debate and controversy surrounding the implementation of universal LQTS screening in the United States.
Unlike WAP-enabled phones, the screen on the Visor is large enough to display multiple lines of text and graphics.
The pooled shRNA library screen yielded high quality and reproducible data, as supported by multiple lines of evidence.
This assessment is based on multiple lines of evidence.
She messaged her thoughts to me over multiple lines.
