Sentence examples for multiple limitations including from inspiring English sources

Although autologous bone graft is a safe and effective way to provide bone cells still it has multiple limitations including donor site morbidity, limited cells quantity, requirement of a second surgical procedure with frequent consequences of pain, and complications [ 84– 86].

This study had multiple limitations, including the cross-sectional design of NHANES, which limits any conclusions regarding causality.

Conventional methods to delivery therapeutic agents for SCI, for example, administration and intravenous infusion have multiple limitations, including elevated risk of infection, low effective concentration, quick drug degradation and reduced tissue penetration11.

However, the original analytic strategy proposed by Campbell and Fiske for conducting an MTMM analysis has been shown to have multiple limitations, including ambiguity about what constitutes satisfactory results and how to extract underlying trait and method factors from the correlation matrix [ 25].

Recently, the Prostate Cancer Results Study Group compared radical prostatectomy, radiotherapy, cryotherapy, and high intensity focused ultrasonography, but interpretation of their results is difficult owing to multiple study limitations, including the use of differing definitions of biochemical recurrence as the endpoint.

However, currently available methods for quantifying apoptosis have various limitations including multiple, sometimes cell-damaging steps, the inability to quantify live, necrotic and apoptotic cells at the same time, and non-specific detection (i.e. "false positive").

The use of multiple analyses to compare the different structural changes has limitations, including the risks of finding significant results only by chance.

Their limitations include multiple food and drug interactions and need for frequent monitoring and dose adjustments.

Other limitations include multiple assessors and therefore potential variation in the wording or prompting provided to study participants in the recall of health service utilisation.

Study limitations included multiple protocol violations and imbalances in some baseline characteristics (e.g., more ESA-treated patients had relapsed cancer and were smokers).

Other limitations include difficulties recognizing multiple instances of the same device (e.g. more than one connected thermostat); and external interference from powerline noise which can confuse the device classifier.