Sentence examples for multiple ligands to from inspiring English sources
How binding of multiple ligands to receptors shapes dose responses.
Nature makes extensive use of polyvalency the simultaneous binding of multiple ligands to multiple complementary receptors.
The simultaneous binding of multiple ligands to multiple cellular receptors can lead to receptor clustering.
AutoDock does not allow multiple ligands to be docked with the same protein at the same time.
ERs have a large and flexible binding pocket that allows for multiple ligands to bind, including steroids, phytoestrogens, and xenobiotics.
The monolayers have proven particularly significant in studies of ECM proteins that present multiple ligands to a cell.
The possible effects of both single and multiple ligand-to-scaffold distributions will be further examined in the next section.
On the other hand, the ability to bind multiple ligands at a given site is largely derived from hinge-based motions.
Stem cell differentiation is regulated by complex repertoires of signaling ligands which often use multivalent interactions, where multiple ligands tethered to one entity interact with multiple cellular receptors to yield oligomeric complexes.
Compared to optimizing the balance of affinities and the wider selectivity, an even greater challenge for medicinal chemists when confronted with the challenge of designing multiple ligands is to obtain physicochemical and PK properties consistent with developing an oral drug.
Finally this study addressed the interdependence of multiple ligands known to activate GIRK channels.
