The indirect method of analysing BPA is standard for urine, and has been used in multiple laboratories that have analysed human serum [ 46, 56].
This is supported by WGS of six M. tuberculosis H37Rv strains from multiple laboratories that showed little change after years of repeated sub-culturing, suggesting genomic stability during in vitro culture [ 20].
That a marker of a differentiated normal mammary epithelial cell could enrich for cells with TIC activity in the context of breast cancer is also supported by recent evidence from multiple laboratories that, in BRCA1 basal-like tumors, the TIC population arises from the luminal lineage [ 63- 65].
Reports from multiple laboratories reveal that the functional integrity of the immune system is of paramount importance to the survival of the individual after infection or injury.
However, studies from multiple laboratories reported that TPC overexpression promoted lysosomal Ca2+ release (Brailoiu et al., 2009; Calcraft et al., 2009; Pitt et al., 2010; Ruas et al., 2010; Grimm et al., 2017), suggesting that the relatively small Ca2+ permeability of TPCs is physiologically significant.
Such a concept is supported by preclinical data from multiple laboratories showing that RB loss is associated with sensitivity to chemotherapeutic agents.
Despite variation in stem cell isolation strategies, studies from multiple laboratories report that BCSCs express very little ERA compared to the tumor of origin or to breast cancer cell lines [ 9, 10, 38, 39].
These studies from multiple laboratories reveal that while the half-life of hepatocytes in the healthy adult liver is approximately half a year, the median half-lives of infected hepatocytes in patients with chronic hepatitis B are 257 h (=10.7 days) (n=9, range 112 762 h) and 7 days in patients with chronic hepatitis B under lamivudine treatment.
Natural extracellular matrix factors such as collagen, laminin, fibronectin, etc., can be utilized in the culture of these cells [ 2] and in the performance of multiple laboratory procedures that require the cells to remain attached to the culture vessel, for example immunocytochemical procedures.
A representative example of this approach is the SIGla: an adaptive open source LIMS for multiple laboratories [ 18] that provides the integration between a generic information system and several available workflow engines using standard files.
In addition, variations in reporting requirements across states may be an extra cost to laboratories that serve multiple health jurisdictions.
