Sentence examples for multiple knottin loops from inspiring English sources
These findings expand the potential of the cystine-knot scaffold for future studies where multiple knottin loops can be simultaneously engineered to bind to exogenous targets.
In the current study, our goal was to explore the potential to introduce an additional, but distinct, integrin-binding epitope within a structurally-adjacent knottin loop.
These results have important implications for future polypeptide engineering efforts, where multiple loops of a knottin peptide could be evolved to bind with high affinity against a molecular target of interest.
Importantly, we demonstrated that multiple loops of a knottin peptide, comprising 21 non-native amino acid residues, can be engineered to bind with high affinity to integrin receptors, and the resultant peptide can be used as a probe for non-invasive molecular imaging applications.
By using the multi-pass method they unroll and rearrange the multiple nested loops.
These arrays can intersect each other, and form multiple closed loops.
Bifurcation analyses on feedback loops indicate that multiple feedback loops are coordinated to modulate sporulation efficiency.
Hypothalamic inflammation influences the set points of multiple homeostatic loops.
The Arabidopsis circadian clock is composed of multiple feedback loops.
The original loop is one part of interconnected multiple feedback loops that contain the morning- and evening-expressed clock proteins.
Among these patients, 57.75% had only single tortuous loops, while in 26.76% multiple tortuous loops were observed.
