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Originally identified as allelochemicals involved in plant parasite interactions, more recently, Strigolactones (SLs) have been shown to play multiple key roles in the rhizosphere communication between plants and mycorrhizal fungi.
Nm23 plays multiple key roles in tumor metastasis, oncogenesis, proliferation, development and differentiation.
Given its ER membrane localization and mainly cytosolic topology [10], Usa1 has the potential to play multiple key roles in the ERAD pathway.
Three muscle-specific miRNAs (miR-1, miR-133, and miR-206), with multiple key roles in the control of muscle growth and differentiation, have been the focus of intense research.
To address this need, we focused initially on occupancy by TAL1, since this TF plays multiple key roles in hematopoiesis and is needed for differentiation of erythroid progenitor cells into maturing erythroblasts [ 30].
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While they are undoubtedly essential to sustaining life and meeting the energy requirements of the cell through oxidative phosphorylation, they are now regarded as highly dynamic organelles with multiple functions, playing key roles in cell survival and death.
Our study demonstrates that by 1 hour, TGF-β suppresses the expression of multiple genes that play key roles in regulating cell cycle progression.
However, these genes have key roles in multiple cell biological events, and therefore their downregulation in normal cells would have adverse effects on normal cell functioning [18].
Akt, a serine/threonine-specific protein kinase playing key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration, was also upregulated by 18 h with significant difference between all three groups (p < 0.05).
In this regard, the PKC family is attractive for targeting, because it is comprised of a family of isoforms that play key roles in multiple cellular processes and can contribute to cellular transformation.
MAPK-activated protein kinase 2 (MK2), a direct substrate of p38 MAPK, plays key roles in multiple physiological functions in mitosis.
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multiple essential roles
multiple key features
multiple key Republicans
multiple professional roles
multiple key targets
multiple key proteins
multiple key stages
multiple key pools
multiple key steps
multiple key properties
multiple key players
multiple key changes
multiple key processes
multiple key variables
multiple key elements
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