Sentence examples for multiple key proteins from inspiring English sources

Observations for the in vitro model of fed tick vector relative to the unfed tick vector reveal abundance changes in multiple key proteins that lead to changes in B. burgdorferi cell membrane, cell metabolism, and other basic functions, which enable adaption to its new environment.

To understand if the observed reduction of BECN1 in AD patients is an isolated finding or if it could causes a more general disturbance of the autophagosomal system (similar to our in vitro findings) we measured multiple key proteins involved in autophagy (Fig. 7A) in human brain samples.

Thus, the miR-23a/b and miR-27a/b may suppress multiple key proteins in the apoptosis pathway in human brain development.

In response to DNA double-strand breaks, ATM phosphorylates multiple key downstream proteins including p53 and BRCA1/2, the most common sporadic and inheritable mutated genes in breast cancer [ 6], thereby orchestrating complex signaling pathways involved in cell cycle arrest, DNA repair, senescence and apoptosis [ 7].

Considering that cells in advanced breast cancers can have multiple mutations and genetic alterations, it is likely that therapeutic combinations targeting multiple pathways or key proteins will be more effective than single or nontarget-specific agents.

Transport across photosynthetic and mitochondrial membranes can be described as multistep hopping among multiple redox cofactors, and long-distance hopping via multiple aromatic residues in key proteins is known as well.

Thereby NF-kB could contribute to the malignant phenotype of cHL cells due to the stabilization of key proteins of multiple signaling pathways by HSP90 upregulation.

Specifically, we determined protein levels of DDX6, a DExH/D-box RNA helicase with multiple roles in mRNA metabolism, and of AGO2 and TNRC6A, two key proteins of the microRNA pathway.

Interestingly, we found miR-29 to target multiple members of the BH3-only family of genes, which are key proteins necessary for Bax activation during apoptosis.

TBI could conceivably trigger multiple molecular pathways that result in the overproduction and aggregation of a number of key proteins that form pathological aggregates in neurodegenerative diseases.

In fact, multiple horizontal gene transfer events have been implied through the phylogenetic analysis of the key proteins involving photosynthetic light reactions [ 26].