Sentence examples for multiple key effectors from inspiring English sources

Together with our previous results [ 20], it is demonstrated that low expressions of miR-17 and miR-92 families promote cisplatin resistance by acting on multiple key effectors along triggering the inhibition of DNA synthesis and the repair of DNA damage, and this is achieved in part by targeting TGFβ R2, CDKN1A and RAD21 (Fig.  7).

Then, a library was built of molecular effectors to potentially target multiple key gene products involved in human disorders that display complex pathological networks.

Hepatic stellate cells (HSCs) are key effectors during the development of liver fibrosis.

We propose that H3K27me3 demethylation and HSFA2 activation might be key effectors downstream of heat sensing in plants.

Therapeutic numbers of antigen-specific cytotoxic T lymphocytes (CTLs) are key effectors in successful adoptive immunotherapy.

Thus, auto reactive B cells represent key effectors to be investigated.

Introduction Neutrophils are key effectors in the host´s immune response to sepsis.

Modulating the key effectors within the tumor stroma is an area ripe for drug development.

Caspases are key effectors of apoptosis.

The transcription factor FOXO3a is one of the key effectors of the PI3K-Akt signaling pathway.

SFs are key effectors in the pathogenesis of RA.