Sentence examples for multiple joint tissues from inspiring English sources
In the present study, sections of murine stifle joints with naturally occurring (aged animals) and surgically induced (destabilized medial meniscus, DMM) OA were examined using a newly developed histological grading scheme that includes quantitative measurements and semiquantitative grades to evaluate multiple joint tissues.
This picture of mechanopathology contributing to pathology in multiple joint tissues that interact with one another to accelerate that pathology represents the picture of fully developed disease.
Osteoarthritis (OA) is a degenerative joint disease (DJD) that impacts multiple joint tissues (i.e. subchondral bone, synovium), but is typically associated with a deterioration of articular cartilage.
A limiting aspect of this study was that the tissue lysates for gene expression analyses were prepared from the multiple joint tissues (including cartilage, subchondral bone, meniscus, synovium, joint capsule, and growth plate) instead of just from the articular cartilage.
These and many other relevant findings in vitro (discussed below) clearly show that estrogen influences the activity of all joint tissues through complex molecular mechanisms acting at multiple levels.
Progression of the autoimmune response involves the development of autoreactive Th1 cells, their entry into the joint tissues, and future recruitment of inflammatory cells through multiple mediators.
Although articular tissues have long been considered unresponsive to estrogens or their deficiency, there is now increasing evidence that estrogens influence the activity of joint tissues through complex molecular pathways that act at multiple levels.
Progression of the autoimmune response involves the development of autoreactive Th1 and Th17 cells, their entry into the joint tissues, and the subsequent recruitment of inflammatory cells via multiple mediators [ 4].
Some patients require multiple joint replacements.
These controls showed low joint inflammation and no joint inflammation in their joint tissues.
Joint hypermobility is also common, including congenital hip dislocation and recurrent or multiple joint subluxations.
