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The CHIKV acute stage typically consisting of fever, rash and multiple joint disorders is frequently followed by a chronic stage, mainly characterized by peripheral joint disorders [ 1- 9], which it is estimated can persist up to five years [ 10].
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Patients with congenital disorders have multiple joint contractures involving more than one limb that are usually nonprogressive.
This was initially indicated by observations that infants who experience decreased foetal movement in utero due to neuromuscular disorders present a range of skeletal anomalies including multiple joint fusions, craniofacial abnormalities and thin hypo-mineralised bones [ 2, 3].
The widespread changes in bone, the frequent presence of multiple joint involvement and the link with obesity has lead to the suggestion of a systemic musculoskeletal disorder, in contrast to the traditional cartilage-first hypothesis.
Joint disorders in the jaw might be a sign of osteoporosis.
Temporomandibular joint disorders.
(d) No temporomandibular joint disorders.
Lumbar spine disorders were the most common non-traumatic disorders, followed by tendon and joint disorders.
(e) history of chronic illness, systemic joint disorders, and collagen disorders.
Some patients require multiple joint replacements.
Occlusal adjustment for treating and preventing temporomandibular joint disorders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com