Sentence examples for multiple isoforms from from inspiring English sources

Alternative splicing (AS) generates multiple isoforms from a single precursor mRNA, and these isoforms usually exhibit different tissue distributions and functions.

At least 75% of our genes undergo some degree of alternative splicing to generate multiple isoforms from one gene.

While specialized functions of individual BORIS isoproteins remains to be documented, it is likely that expression of multiple isoforms from the human BORIS locus is biologically important.

Organisms where we identified zero or a single putative eIF4G-encoding locus may contain additional highly divergent loci missed by our analysis or may encode multiple isoforms from a single locus, as is the case in C. elegans [22].

One alternative model to gene family expansion is to generate multiple isoforms from a single gene.

Not only APA can produce multiple isoforms from the same genes, but alternative splicing also can generate different transcripts from the same genes.

Our results demonstrate that multiple isoforms expressed from human BORIS gene encode isoproteins that can bind DNA and function as transcription factors.

Further evidences on the existence of multiple isoforms come from the conflicting data on their tissue and cellular distribution.

In addition, messenger RNA sequencing can be utilized for the identification of hybrid transcripts and quantitation of multiple isoforms resulting from alternative splicing.

Their identity was confirmed using IFI16 siRNA studies, and multiple isoforms, arising from differential splicing, have been reported previously, although functional differences have not been described (41).

This method does not exclude hits to multiple isoforms produced from the same gene, although we inspected BLAST results for our 29 genes and found that most hits were to products of distinct genes, which we consider to be potential paralogs.