Sentence examples for multiple ion channel from inspiring English sources

Vulnerable substrate and multiple ion channel disorder in a diseased heart will be new targets for antiarrhythmic therapy.

Moreover, STX1A also interacts with and co-regulates multiple ion channel types and neurotransmitter transporters (e.g., sodium ENaC, potassium KCNB1, and dopamine DAT; Table S7).

In summary, the present study provides the first information that multiple ion channel currents are present in cultured human cardiac fibroblasts, the patterns and properties of these ion channel currents differ from those observed in human cardiac myocytes.

These tissue models have been used to study the effects of single and multiple ion channel blockade on Purkinje fibers.

We collected multiple ion channel data (hERG, Na, l-type Ca) on 31 drugs associated with varied risks of TdP.

Cardiac myocytes have multiple ion channel types (see Fig.  1), and the human channels of each type can be studied in isolation in cells overexpressing single types.

We simulated a population of neurons in which expression levels of a neuropeptide receptor and multiple ion channels were simultaneously varied within a physiological range.

Some investigational agents are directed at multiple ion channels, or are designed to be analogs of amiodarone.

In this model we considered the ATP release process and the activities of multiple ion channels and purinergic receptors.

"... We developed a multiscale model of primary motor cortex, ranging from molecular, up to cellular, and network levels, containing 1715 compartmental model neurons with multiple ion channels and intracellular molecular dynamics.

Since its development by Sakmann and Neher (1, 2), the patch clamp has become established as an extremely useful technique for electrophysiological measurement of single or multiple ion channels in cells.