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However, the response to anti-VEGF drugs in DME is not as robust as in proliferative diabetic retinopathy, and many patients with DME do not show complete resolution of fluid despite multiple intravitreal injections.
To describe the clinical course and ancillary findings of 3 patients with choroidal melanoma who inadvertently received multiple intravitreal injections of bevacizumab for a presumed diagnosis of choroidal neovascular membrane.
To evaluate the effects of multiple intravitreal injections of anti vascular endothelial growth factor (VEGF) agents on the thickness of the retinal nerve fiber layer (RNFL) in patients with wet age-related macular degeneration (ARMD).
To evaluate the biologic activity of multiple intravitreal injections of ranibizumab in patients with center-involving clinically significant diabetic macular edema (DME) and to report any associated adverse events.
He underwent multiple intravitreal injections of bevacizumab and triamcinolone for the treatment of CRVO-associated macular edema.
There was no significant difference between the two groups in number of eyes requiring multiple intravitreal injections of antifungals (molds 50%, yeast 33%, p = 0.229).
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To evaluate the long-term safety and efficacy of multiple intravitreal ranibizumab injections (Lucentis, Genentech, Inc., South San Francisco, CA) administered at the investigator's discretion in patients with choroidal neovascularization secondary to age-related macular degeneration.
OBJECTIVE: To evaluate the long-term safety and efficacy of multiple intravitreal ranibizumab injections (Lucentis, Genentech, Inc., South San Francisco, CA) administered at the investigator's discretion in patients with choroidal neovascularization secondary to age-related macular degeneration.
To our knowledge, this is the first case report of macular hole formation secondary to an RPE tear and contraction of the RPE edge and subretinal fibrosis following multiple intravitreal aflibercept injections.
Over the next several months, the patient was given multiple bilateral intravitreal injections and continued on systemic oral valacyclovir 1 g three times a day.
Majority of patients had prior therapy with multiple intravitreal anti-VEGF injections.
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