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In the multiple intraperitoneal administrations, necrosis at the injection site was not observed.
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To induce insulin-dependent diabetes, STZ is typically given through a single intravenous administration or through multiple low-dose intraperitoneal administrations (Deeds et al., 2011).
Puromycin can be given by multiple intraperitoneal injections with initial administration of 10 mg/kg followed by 40 mg/kg every 4 weeks or as a single intravenous dose of 50 mg/kg to cause puromycin aminonucleoside-induced nephrosis (PAN).
Mice were pre-treated with multiple low doses of STZ, followed by intraperitoneal administration of the REG3B GLP-1-expressing vectoREG3B GLP-1-expressingse levels weREG3B GLP-1-expressingks after vector andinisthetion.
Intraperitoneal administration of kainic acid transiently induced the c-fos mRNAs in medaka brains.
Intraperitoneal administration decreases tumor proliferation and shrinks xenografts in vivo.
Intraperitoneal administration of pentoxifylline (200 mg/kg) abrogated this effect.
This represents a 24-fold increase in exposure for tissues at peritoneal surfaces after intraperitoneal administration.
Also, post-training, intraperitoneal administration of CB1R agonist ACPA (0.005-0.05 mg/kg) impaired both memories.
In vivo, they were determined by intraperitoneal administration of three doses in the guinea pig.
A majority of the compounds exhibited significant antiparkinsonian activity after intraperitoneal administration.
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