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Studies with multiple intervention groups will be included.
For trials involving multiple intervention groups, we followed the approach described in Higgins 2011b.
Trials using a factorial design with multiple intervention groups were eligible for inclusion.
For trials with multiple intervention groups or varying doses of iron, we extracted data for eligible comparison groups.
If trials with multiple intervention groups receiving identical treatments are found, the intervention groups will be combined to create a single pairwise comparison.
If a trial with multiple intervention groups was included in a meta-analysis, we combined the groups for a single pairwise comparison.
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Of the high quality studies reporting significant positive outcomes for health literacy (8 studies) [ 22- 24, 35, 42, 43, 50, 57], three included a group education intervention, two individual counseling, one written, one telephone and a multiple intervention (group education with mail/telephone follow-up).
Where multiple intervention or control groups were presented, we only included those groups which allowed us to isolate the effect of tree nuts.
29 In cases where there were multiple intervention or control groups, we combined either intervention or control groups to create single pairwise comparisons with the aim of diminishing the unit-of-analysis error.
For the main comparison, if multiple intervention and/or control groups were compared in the same study, the respective groups were combined in pairs with RevMan software or considered separately when the distinction was relevant.
If necessary, we will combine results of multiple intervention or comparison groups so that only single pair wise comparisons are made.
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