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fax-1 mutations affect multiple interneuron types.
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Accumulating evidence indicates that recruitment of GABAergic cells is highly diverse among interneuron types.
The exquisite architecture of cortex incorporates a myriad of inhibitory interneuron types.
This situation has changed dramatically in recent years with the advent of novel tools for targeting genetically distinct interneuron types so their activity can be observed and manipulated.
At the moment, we could not assign type-5, type-6, and type-7 interneurons to previously described interneuron types.
These interneurons correspond well with previously described CCK-positive intypesuron thats thareare known to innervate CA1 pyramidal dendrites [25], [26].
For the remaining interneurons, however, electrophysiological criteria were not sufficient for classification of all interneuron types in the dentate gyrus.
Primary interneurons have mutual synaptic contacts (see below) and also form synapses on two other interneuron types.
Thus, the various cellular characteristics suggest that different interneuron types contribute differentially to cortical network operations.
DOI: http://dx.doi.org/10.7554/eLife.08758.021 We next examined projections of the interneuron types.
For example, in turtle cortex, some interneuron types express calbindin, others express neuropeptide-Y, while parvalbumin (PV -positive interneurons aPV -positiveabsent.
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