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For example, cooperative binding to the promoter, or binding to a promoter with multiple internal states, will modify the binomial switching term.
This capacity of achieving multiple internal states is at the core of a plethora of regulatory mechanisms, often associated to small genetic circuits, including both switches [5], [6], [7], [8], [9] and oscillators [10], [11].
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Bistable and multistable (and hence discrete) hysteretic switches, enabling cells to adopt multiple internal expression states in response to an external input have a pivotal impact on biological systems, ranging from cell-fate decisions to cell-cycle control [26].
Using primate neurophysiology and human magnetoencephalography, we here recover a single-trial index of PFC internal states from multiple simultaneously recorded PFC subregions.
In [15], memory state feedback control for singular systems with multiple internal incommensurate constant point delays was demonstrated.
Braverman's external locales have long revealed internal states.
*An 88-year-old man with multiple internal organ failure who had been transferred to Hermann from another hospital.
A broken pelvis, femur and multiple internal injuries kept her bedridden for six weeks.
Difficulties with focus and attention arise from the confluence of multiple internal and external factors.
In both cases the internal states can be physical states.
and in the case of multiple internal seeds, (22).
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