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Given the high density of functional groups within active sites and the presumed need for multiple interconnections to provide optimal positioning of functional groups for transition state interactions, residues that evolved for different functional purposes may end up structurally linked and with the ability to position the same group or groups.
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Hadoc is a document base dedicated to the exploration of basic concepts in Automatic Control (closed-loop performances like stability and precision, or modelling tools like transfer function or frequency plots and the various parameters associated with these models), and to the study of the multiple interconnections between concepts.
Developing three-dimensional space and system arrangements is a challenging and time-consuming task because ship layouts include hundreds or thousands of elements with multiple interconnections and dependencies governed by functional characteristics.
Yet a neuroscientific account of a particular purpose must be extraordinarily complex involving of millions or tens of millions of neurons and their multiple interconnections.
Neurites growth was most obvious around day 6, and multiple interconnections among cells can be seen.
Because of the multiple interconnections and interactions of bone and the immune system, bone is a major target of chronic inflammation in RA and ankylosing spondylitis (AS).
The ecohealth model stems from the generation of health knowledge and the multiple interconnections between the different components of the ecosystem.
In comparison, RT2 Dll4 +/- insulinoma showed a 1.8-fold increase in the density of PECAM-positive areas (p < 0.05) and formed atypical networks lacking vessel hierarchy or symmetry but displaying pronounced branching and multiple interconnections.
Considering the multiple interconnections between bodies, technologies, and people across different places and spaces, and how these are in a constant state of flux, creates new opportunities for enabling practices in both design and rehabilitation.
Although there are a wide range of approaches to systems dynamics modelling, [ 21] these generally share the premise that complex systems behavior results from the interplay of feedback loops, multiple interconnections, non-linearities, time delays, stocks, and flows that all occur within a system, which can be mapped and, in some circumstances, modelled using computer simulation [ 22].
We present several typical scam campaigns and show the connections between clusters, which are possibly run by the same group of scammers due to multiple strong interconnections among scam emails belonging to the same cluster.
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