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The clamp loader, as we have seen, interacts with the clamp through the cooperative action of multiple interactions that appear to be weak.
The utilization of carefully selected statistical designs is essential to unravel the multiple interactions that do occur and to optimize food formulation and processing.
Detailed energy decomposition analyses have shown that every interaction between two molecular systems involves a combination of multiple interactions that makes the interaction strong enough to maintain the stability of the molecular structures [6].
Our study illustrates that in the proton shuttle procedure, the histidine is not working by itself alone, but with the collaboration of environmental residues through the multiple interactions that affect the pKa value of histidine.
It appears that there are multiple interactions that lead to the AR, most likely involving carbohydrates.
Trial-based designs may under-recognise the weak boundaries separating context and intervention, and the multiple interactions that take place between them.
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A Greenpeace review of research on geological repositories, published in September, listed several scientific caveats, including a lack of understanding of the multiple chemical interactions that may occur; doubts about the accuracy of computer modeling over long time scales; and the possibility of an earthquake or other disturbance to the site during the repository's life.
This model was expanded to capture the multiple SNP interactions that characterized these simulations.
Previous studies have revealed multiple molecular interactions that can now explain the host restriction of L. monocytogenes, as discussed in several excellent reviews.
High-resolution crystal structures of parkin's RING0-RBR domains, which lack the Ubl domain, revealed multiple domain domain interactions that regulate parkin activity (Chaugule et al, 2011; Riley et al, 2013; Trempe et al, 2013; Wauer & Komander, 2013).
However, the nutrients/food components responsible for the effects are difficult to ascertain due to multiple nutrient interactions that would need to be isolated for study and to the possible substitution of nutrients known to increase risk for certain chronic diseases, for example, saturated fats.
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