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A generalized mobility/impedance-power flow mathematical model is developed to analyze the dynamical behaviour of a complex coupled system consisting of any number of substructures with various configurations and multiple interaction interfaces.
Motivation: Eukaryotic proteins are highly modular, containing multiple interaction interfaces that mediate binding to a network of regulators and effectors.
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Therefore, our results suggest that ZNF198, through its multiple protein-protein interaction interfaces, helps to maintain the intact LCH complex on specific, non-REST-responsive promoters and may also prevent SUMO-dependent dissociation of HDAC1.
Ubiquitous computing with multiple interaction devices requires new interface models that support user-specific modifications to applications and facilitate the fast development of active workspaces.
We find that in length-deviant domain superfamilies, additional lengths are associated with multiple roles such as substrate specificity, regulation, stability, generating interaction interfaces to form higher order complexes involving multiple domains in multimeric organizations etc.
In this paper, we present an interaction system we developed to support collaborative work on large high-resolution displays using multiple interaction devices and scalable, distributed user interface widgets.
With regard to the retrieval of molecular interaction data, the Proteomics Standard Initiative Common QUery InterfaCe 64 provides a standardized web service to access multiple interaction resources such as IntAct 65 and STRING.
Another way to define the interaction similarity is through the similarity of the corresponding interaction interfaces.
Our simple assumption behind extracting similar interaction interfaces from 3D Complex is that two structurally similar protein complexes are likely to have structurally similar interaction interfaces.
Proteins supplementary data of Kim et al. (2006) was used to obtain structurally resolved singlish interaction interface hubs (≥ 5 interaction partners + at most 2 interaction interfaces).
The interaction interfaces that are critical for ring formation (i.e., the head-to-head dimer interface and the head-domain coiled-coil interface) are bothead-domain coiled-coil
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