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Moreover, since proteins often contain multiple interaction domains, it is the sum of these interactions that defines the protein's position in the network.
Cbl proteins are scaffold proteins with multiple interaction domains.
We also investigated a possible selective pressure for more protein-protein interactions, requiring multiple interaction domains, in large proteins.
Thus, a requirement for multiple interaction domains may be considered to act as a balancing selective force, partially offsetting the general fitness benefit of minimizing protein size.
PKD serine kinases are large proteins comprising multiple interaction domains, including both protein−protein- and protein−lipid-binding regions, and have the potential to function as scaffolds.
It was shown that P1a binds to integrin subunit β4 via multiple interaction domains including its N-terminal ABD (de Pereda et al. 2009; Koster et al. 2004; Rezniczek et al. 1998).
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The presence of multiple RNA interaction domains suggests intimate and potentially multiple roles for RNAs in the control of H3K4me3 and programming active chromatin.
Previous studies have shown that Rolling pebbles (Rols)/Antisocial (Ants), a scaffold protein with multiple protein interaction domains, is involved in sustaining fusion beyond the bi/trinucleate precursor stage.
UNC-13/Munc13 UNC-13/Munc13 UNC-13/Munc13rotein interaction domains, and have been linked to nearly all asproteins presynapticontainse.
Furthermore, BBS1, BBS2, BBS4, BBS7, BBS8, and BBS9 contain multiple protein protein interaction domains.
Syntrophins are adapter proteins that use multiple protein interaction domains to localize a variety of signaling proteins to specific intracellular locations.
More suggestions(15)
multiple interaction possibilities
multiple interaction models
multiple source domains
multiple interaction mechanisms
multiple interaction blocks
multiple interaction mixtures
multiple interaction networks
multiple protein domains
multiple interaction modes
multiple treatment domains
multiple fluid domains
multiple interaction surfaces
multiple interaction sites
multiple interaction instances
multiple interaction contexts
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