Sentence examples for multiple interacting loci from inspiring English sources

While only two interacting loci are considered here, Equation 8 is correct for multiple interacting loci (for derivation repeat the above calculations for q ˙ i 1 = q ˙ i j k 111 + q ˙ i j k 110 + q ˙ i j k 101 + q ˙ i j k 100 ).

A general method is described for estimation of the power and sample size of studies relating a dichotomous phenotype to multiple interacting loci and environmental covariates.

For simplicity, we assume haploid sexual organisms, an assumption that often has been made for theoretical analyses involving multiple interacting loci (e.g. [13], [40]).

In this sense, Drosophila brings an impressive toolkit for dissecting multiple interacting loci with individually small effects that affect quantitative developmental traits [16].

By identifying a firm genetic basis for GL independent of litter size or pregnancy load, we establish a foundation for the identification of genes and pathways that regulate GL and timing of parturition, which clearly involves multiple interacting loci.

This study seems to imply a single major locus, but the hypothesis of multiple interacting loci or genetic heterogeneity cannot be ruled out.

While there is evidence of the involvement of environmental risk factors, epidemiological twin and adoption studies also support a genetic component in the etiology of the disease [8], [9], [10] in which multiple interacting risk loci play a role [11].

In this study, GMM demonstrated the existence of loci which affected the phenotype through multiple combinations of interacting loci.

Through genome-wide linkage scans using an F2 intercross population from TH and B6 strains, we identified multiple QTLs and interacting loci linked to hyperlipidemia, hyperglycemia, and obesity phenotypes.

By illustrating the positions of interacting loci, the loci which affect the phenotype through interactions with multiple combinations of genotypes are readily identified; in this case, 50 52 cM and 84 89 cM on LG2, 76 cM on LG5, and 27 cM on LG6.

In this way, master regulons involved in multiple traits (i.e., pleiotropic genes) can be identified, and the amount of epistasis from interacting loci can be uncovered [ 39].