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Alternative approaches inhibiting multiple interacting and interdependent pathways, vertically and horizontally, with two or more molecularly targeted therapies holds greater potential for improved outcomes.
The student's choice of learning style appears to be dependent on multiple interacting and to some extent, confounding factors, most importantly the student's innate learning motivation and preferred learning strategy.
Organizations that design and/or operate complex systems have to make trade-offs between multiple, interacting, and sometimes conflicting goals at both the individual and organizational levels.
Complex interventions have multiple, interacting and context-dependent active ingredients, which are challenging to identify and keep stable [ 56].
In primary care, many patients have multiple, interacting, and compounding physical, psychological, and social problems [ 1, 2].
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The multiple interacting male and female partners and the two antagonistic phosphorylated motifs argue for the presence of mechanisms capable of fine-tuning the PRK signalling capacity to facilitate interactions with different partners and modulate RAC/ROP GTPase activity to mediate polarized growth throughout the long pollen tube growth journey in the pistil.
The simulation and analysis of the cascades leading to blackouts are extremely intricate due to various time scales, multiple interacting automatic and human-driving actions, and the large set of possible countermeasures.
With respect to the substrates of tyrosine phosphorylation and Crk transformation, a great deal of attention has been placed on the p130Cas/HEF1/Efs proteins, a family of non-enzymatic docking proteins that contain multiple interacting domains and serve as important anchoring points for protein-protein interactions [ 46, 91].
A general method is described for estimation of the power and sample size of studies relating a dichotomous phenotype to multiple interacting loci and environmental covariates.
Our results show that it is possible to infer regulatory links between multiple interacting TFs and their target genes even from a single relatively short time series and in presence of unmodelled confounders and unreliable prior knowledge on training network connectivity.
Most design problems have multiple interacting constraints and levels of analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com