The reference scale consists of 5 color intensity grades.
The intensity grades of these peritumoral findings were severe; however, the intensity grade of the monocyte infiltration (M) was slight to moderate in this TG-A.
Using an empirically derived and validated grading system, severity is divided into five categories: grade 0 (pain free), grade 1 (low disability, low-pain intensity), grade 2 (low disability, high-pain intensity); grade 3 (high disability, moderately limiting pain); and grade 4 (high disability, severely limiting pain).
1Headache intensity graded as 0 = none; 1 = mild; 2 = moderate; 3 = severe.
Only 6%% of the TMD cases reported high disability and high pain intensity (Grade 3, 4).
An intensity grading scale was used to grade the severity of the adverse events.
As many of the tumors showed more than one intensity grade, each intensity grade was evaluated according to percentage.
Grade I represents "low disability and low intensity pain", Grade II is "low disability-high intensity", Grade III represents "high disability-moderate intensity" and Grade IV reflects "high disability-severely limiting" pain.
Pain severity can be graded in four hierarchical classes (Grade I, low disability – low intensity; Grade II, low disability – high intensity; Grade III, high disability – moderately limiting; Grade IV, high disability – severely limiting).
This is a 7 item questionnaire resulting in four hierarchical categories: Grade I, low disability - low pain intensity; Grade II, low disability - high pain intensity; Grade III, high disability - moderately limiting; Grade IV, high disability - severely limiting.
Without prior knowledge of the clinical data, two of the authors independently graded the staining intensity as follows: grade 0, no staining or less than 10% of tumor cells; grade 1+, ≥10% tumor cells with weak staining intensity; grade 2+, ≥10% tumor cells with moderate staining intensity; and grade 3+, ≥10% tumor cells with strong staining intensity.
