Additionally, the Radiation Therapy Oncology Group study 95-17 [ 23] demonstrated the ability of multiple institutions to effectively perform similar interstitial catheter-based implants.
Furthermore, patients with lung adenocarcinoma with c-MYC gain, even in early stage, appear to have an increased risk of disease progression and death, which merits further prospective evaluation across multiple institutions to validate the clinical utility of c-MYC gains in this disease setting and to determine whether these patients might benefit from additional first-line therapy.
However, the collection of data from multiple institutions for chart review analysis is labor-intensive and costly, thereby limiting its applications in large-scale inter-hospital comparisons.
Many teach at multiple institutions to generate income.
12 The MERSQI framework provides a measure of trial size (single or multiple institutions), validity of assessment instruments used, and the Kirkpatrick level of outcome measures used (a taxonomy for classifying training programmes).
Confirmation of our findings in a larger cohort of LGSC will therefore require participation by multiple institutions or establishment of a worldwide registry.
The strengths of our study include data from a large number of babies from multiple institutions and use of a consecutive sample of VLBW infants at each institution, thereby minimizing selection bias.
After a central pathological review and search of the medical records from multiple institutions, a total of 572 patients were retrospectively evaluated.
At the conclusion of the trial, analysis will include local as well as multi-institutional outcomes comparisons between intervention and control patients, combining data from multiple institutions performing trials of patient navigation funded by the National Cancer Institute, under the multi-institutional granting structure.
Future research on this topic should involve multiple institutions, comparing universities of different types, sizes, and geographic locations.
