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Furthermore, even with multiple injections in SCID mice, AV reovirus did not induce black tail syndrome or myocarditis.
Worse than that, the proportion of using multiple injections in one prescription was as high as 39.90% overall.
More than 86% and 72% patients with genotypes 3a and 3b respectively had received multiple injections in past.
A study comparing injections of bone marrow in 14 and cortisone in 65 patients reported a need for multiple injections in 57% and 49%, respectively [ 36].
Mice used to examine the kinetics of pHe reduction received multiple injections in a schedule similar to that used with animals in the metastasis experiment.
A total of 64 female volunteers (37 60 years) underwent four sessions of biorevitalization at 3-week intervals, involving multiple injections in the face (external corner of the eye and cheek), neck, décolletage, and back of the hands.
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Simulation results evidenced that the model can predict the effects of different injection parameters, in case of single and multiple injection, in a short computational time.
In summary, multiple injections of LPS resulted in increased Aβ1-42 in the hippocampus and cognitive deficits in mice.
All subjects were also included in the pharmacokinetic population that received multiple injections of CCH in treatment period 2. Efficacy, safety, and pharmacokinetic variables are summarized with descriptive statistics.
Mental models regarding experimental vaccines in clinical trials may share similarities with those of licensed vaccines, for example, in regard to the need for multiple injections; however, participating in placebo-controlled trials is also quite distinct from uptake of vaccines that have already been approved for public licensure [ 27, 31].
Multiple injection valve arrangements (in-series, in-parallel and inner coupling) that give place to FI modes as merging-zones (both symmetrical and asymmetrical), trapping-zone and nested-loop approaches are exposed.
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