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The same could be the case for families with multiple individuals affected by MO.
Our analysis of three families with multiple individuals affected by lymphoma identified several interesting haplotypes shared by distantly related patients.
GCH1 mutations have also been shown to segregate in pedigrees with multiple individuals affected by isolated parkinsonism (Irie et al., 2011).
Germline mutations in the two major breast cancer susceptibility genes, BRCA1 and BRCA2 (MIM113705 and 600185), are frequently found in families containing multiple individuals affected by breast and ovarian cancer [ 1].
Since 1997, kConFab has been recruiting multiple individuals (affected and unaffected by cancer) from families that have presented to FCCs with evidence of high familial risk of breast cancer.
This can be used to identify multiple individuals affected by the same disorder, allowing data from multiple centers to be integrated in the same search in an effective and secure manner.
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Takatani R, Molinaro A, Grigelioniene G, Tafaj O, Watanabe T, Reyes M, Sharma A, Singhal V, Raymond FL, Linglart A, Jüppner H. Analysis of Multiple Families With Single Individuals Affected by Pseudohypoparathyroidism Type Ib (PHP1B) Reveals Only One Novel Maternally Inherited GNAS Deletion.
Along with the need to target the four subgroups above with specific programs, our study highlights the relevance of focusing on younger individuals affected by multiple mental disorders or anxiety disorders concurrent with or without major depressive disorders.
Our study highlights the relevance for mental health service planning of focusing on individuals affected by multiple mental disorders and with clearly critical severity of needs who also find that the help they receive is less than adequate.
However, an individual's serum concentrations can ensue both from regional characteristics (i.e. between-group differences in drinking water concentration of PFOA) and from multiple individual factors affecting the bioaccumulation of PFOA (i.e. within-group differences, such as genetic factors, amount of daily water intake, duration of residence in the area).
In other Cuscuta species (e.g. C. salina), individuals can parasitize multiple individuals simultaneously and affect species richness (e.g. Grewell 2008).
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