Sentence examples for multiple important pathways from inspiring English sources

This finding suggests that our minimized gene signatures are highly representative of multiple important pathways that may be involved in the biological processes underlying the discrimination of normal tissue from breast cancer samples.

Thus, RNA-seq results indicate that HYF127c/Cu-induced oxidative stress could target multiple important pathways involved in cancer, and HYF127c/Cu could be a promising candidate for cancer therapy.

Figure 9 gives further support to the notion that, being an intrinsically disordered hub, p53 is located at the middle of a large and well-developed network of protein-protein interactions, serving as a crucial linker that connects multiple important pathways.

Secreted HB-EGF binds to EGFR triggering the activation of multiple important signaling pathways including the PI3K/Akt/mTORC1 and ERK1/2 pathways.

Furthermore, the involvement of TRIB3 in multiple important signaling pathways makes it an interesting target for cancer therapy.

Because of the role of FKBP5 in the regulation of multiple important biological pathways as discussed in this review, variation in FKBP5 could be of significance in many diseases beyond cancer, and in diseases such as diabetes (Tian, 2005).

Biotin (also known as vitamin H, or B7) is an essential enzyme cofactor involved in multiple important metabolic pathways including fatty acids, amino acids, and carbohydrates in all three domains of life [ 1].

The one gene that did show increased RNAPII occupancy in the fogsk8 mutant, gadd45b, is regulated by multiple important cellular signaling pathways including NF-kB and JNK [47] and is involved in zebrafish somitogenesis [48].

It was also shown that the main underlying mechanisms of action of curcumin were probably based on the modulation of multiple important cellular signaling pathways including NF- κB [ 5, 14].

The main underlying action mechanisms of curcumin are probably based on the modulation of multiple important cellular signaling pathways including NF- κB, TRAIL, PI3K/Akt, JAK/STAT, Notch-1, and JNK [ 5, 14].

Electroporation of human islets should prove a useful approach to aid the study of other important pathways containing multiple members.