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Despite their large size and multiple important functions, our knowledge of vacuole biogenesis and the machinery underlying their amazing dynamics is still fragmentary.
They differed in structure and in size, and showed multiple important functions.
These T cells, present in lesions within organs affected by AAV, have multiple important functions in driving the disease.
A recent series of studies in several organisms revealed multiple important functions of the sirtuin family of proteins in energy metabolism [ 11].
In addition to its role in angiogenesis, VEGF also serves multiple important functions including pro-angiogenesis [ 1], enhancement of vascular permeability [ 2], changing vascular tone [ 3- 7], and promotion of cell survival [ 8], division [ 9], and differentiation [ 10].
36 Insulin has multiple important functions in the brain including the control of food intake (via insulin receptors located in the olfactory bulb and thalamus) and effects on cognitive functions, including memory.
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Since Sirt2 plays a critical role in multiple important cellular functions, our data imply that acupuncture may act through epigenetic changes and subsequent action on their targets, such as miRNA-339/Sirt2/NF- miRNA-339/Sirt2/NF-
In this regard, although the biological importance of SAA in USPC patients is not well understood, previous reports have suggested multiple important biologic functions of SAA.
Integrins bind to various cell surface and extracellular proteins to mediate cell-to-cell matrix adhesion and are involved in multiple important biological functions.
Spleen tyrosine kinase (SYK) is a cytoplasmic protein tyrosine kinase with multiple important regulatory functions in B-lineage lymphoid cells (Mocsai et al., 2010, Uckun et al., 2010a, Uckun et al., 2012, Uckun et al., 2014, Uckun and Qazi, 2010).
Recent findings indicate that the vitamin D endocrine system (VDES), besides multiple other important functions, regulates aging in many tissues, including skin.
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