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The one gene that did show increased RNAPII occupancy in the fogsk8 mutant, gadd45b, is regulated by multiple important cellular signaling pathways including NF-kB and JNK [47] and is involved in zebrafish somitogenesis [48].
It has recently drawn much attention due to its involvement in multiple important cellular processes.
It was also shown that the main underlying mechanisms of action of curcumin were probably based on the modulation of multiple important cellular signaling pathways including NF- κB [ 5, 14].
The main underlying action mechanisms of curcumin are probably based on the modulation of multiple important cellular signaling pathways including NF- κB, TRAIL, PI3K/Akt, JAK/STAT, Notch-1, and JNK [ 5, 14].
Since Sirt2 plays a critical role in multiple important cellular functions, our data imply that acupuncture may act through epigenetic changes and subsequent action on their targets, such as miRNA-339/Sirt2/NF- miRNA-339/Sirt2/NF-
8 Gsα activation, through coupling to various receptors and ligands (PTH, adrenaline, glucagon, adenosine, etc) governs multiple important cellular processes to maintain physiologic functions and development in a variety of tissues.
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The β-NAD+-dependent Nε-acyl-lysine deacylation reaction catalyzed by sirtuin family members has been increasingly demonstrated to be important in regulating multiple crucial cellular processes and has also been proposed to be a therapeutic target for multiple human diseases.
Mitochondria have multiple roles in important cellular functions, including the production of adenosine triphosphate (ATP), cell signalling, cell growth, cell cycle progression and cell death (Raimundo [2014]).
Finally, even when AID expression/activity is being controlled by multiple mechanisms, one important cellular mechanism, which determines the target specificity of AID, still must function properly.
Such composition of domains suggests that Eukaryotic members of COG3680 are involved in interactions with multiple partners, which implies an important cellular function.
Another report demonstrated that the reduction in cell surface ANXA2 expression in response to changes in interferon gamma levels leads to reduced prostate cancer cell invasion[28], suggesting that the cell surface translocation of ANXA2 may be an important cellular process for multiple types of cancers[10].
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multiple vital cellular
multiple critical cellular
numerous important cellular
multiple important legal
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multiple important bacterial
multiple important regulatory
multiple important potential
multiple important biological
multiple important methodological
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