Sentence examples for multiple immune derangements from inspiring English sources

111 Patients with advanced disease (stage IIB IVB) may have disseminated disease into lymph nodes and other organs, and may exhibit multiple immune derangements necessitating systemic therapy.

She is severely disabled – she has multiple immune disorders – and uses a wheelchair, owing to a spinal condition.

SSc is a clinically heterogeneous and complex disease that is characterized by vascular dysfunction, vascular and extravascular fibrosis, and characteristic immune derangements, and for which few treatment options are available.

BCG effect is mediated by multiple immune cells.

TGF-β regulates immune responses and maintains immune homeostasis through its impact on multiple immune cell lineages.

Early efforts to profile multiple immune effector functions of single immune cell function used ICS FFC.

20 31 All attempts to find a 'magic bullet' to restore immune derangements during sepsis and improve the outcomes have failed, highlighting the complexity of the immune response, including a marked intrapatient variability in terms of magnitude of response, timing and trajectory and our continued lack of full understanding.

Such immune derangement may contribute to the rapid progression of and high mortality associated with this disease.

It is therefore reasonable to postulate that certain genetic backgrounds would affect the susceptibility to immune derangement, inflammation, sepsis and AKI, whichever happens first.

Adding to the similarities that exist between septic and non-septic shock in terms of immune derangement, we found similar patterns of Treg kinetics in infected and non-infected patients.

HIV-Leishmania coinfection in these patients may reproduce a vicious cycle leading to persistent immune derangement and paradoxical persistence of low CD4+ cell counts and parasitemia despite HAART and liposomal amphotericin B administration [ 37, 38].